HIV AND INFECTIOUS DISEASES Chronic Progressive HIV-1 Infection Is Associated With Elevated Levels of Myeloid- Derived Suppressor Cells

ثبت نشده
چکیده

Diamond-Blackfan anemia is associated with haploinsufficiency in multiple different ribosomal proteins (but not RPSA) and results in bone marrow failure as well as multiple developmental defects. However, in these patients, there is no evidence of splenic abnormalities, and the current study found no evidence of hematologic abnormalities (or developmental abnormalities) in the patients harboring the RPSA mutations.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Hepatitis E Virus Seroprevalence and Viremia in Hemodialysis and HIV Infected Patients in Iran

Background and Aims: Hepatitis E virus (HEV) infection is usually a self-limited viral disease that causes acute hepatitis and may progress to chronic hepatitis in immunosuppressed individuals. It seems that hemodialysis patients and HIV infected people are more exposed to HEV infection. The aim of this study was to evaluate the extent of HEV infection in hemodialysis and HIV infected patients ...

متن کامل

Paradoxical myeloid-derived suppressor cell reduction in the bone marrow of SIV chronically infected macaques

Myeloid derived suppressor cells (MDSCs), which suppress anti-tumor or anti-viral immune responses, are expanded in the peripheral blood and tissues of patients/animals with cancer or viral infectious diseases. We here show that in chronic SIV infection of Indian rhesus macaques, the frequency of MDSCs in the bone marrow (BM) was paradoxically and unexpectedly decreased, but increased in periph...

متن کامل

Adherence of Islamic values and human immunodeficiency virus prevention

The human immunodeficiency virus (HIV) is lentivirus (subgroup of retrovirus) which causes HIV infection and it acquired immunodeficiency syndrome (AIDS). HIV infection leads to low levels of CD4+T cells through number of mechanisms [1]. Our purpose is to review educative HIV prevention and control as Millennium Development Goal (MDG) and WHO's operational goal. In 2000, when ...

متن کامل

Are the Preventive Services For HHV-8 Necessary in HIV Positive Persons in Central Zone of Iran?

  Background and Objective: It is presumed that human herpes virus 8 (HHV-8) is the necessary cause of all different forms of Kaposi’s sarcoma which is the most common neoplasm in HIV-infected persons. In this study, we wanted to determine the prevalence of HHV8 infection in all the available Isfahan (Central Iran) HIV positive individuals in comparison with healthy blood donor, and also inves...

متن کامل

Numerical analysis of fractional order model of HIV-1 infection of CD4+ T-cells

In this article, we present a fractional order HIV-1 infection model of CD4+ T-cell. We analyze the effect of the changing the average number of the viral particle N with initial conditions of the presented model. The Laplace Adomian decomposition method is applying to check the analytical solution of the problem. We obtain the solutions of the fractional order HIV-1 model in the form of infini...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013